Yes, V-Go should be worn for a full 24 hours, even during sleep.

No, after 24 hours, patients should apply a new filled V-Go because the used device may no longer deliver a steady rate of insulin.

• Patients should choose to wear V-Go on a flat body surface and avoid any folds in the skin.
• Once a location to adhere V-Go is chosen, the area should be thoroughly cleaned with an alcohol swab and let dry.
• Lotion and/or ointment may keep V-Go from sticking to skin.
• Patients should avoid touching the adhesive pad before attaching V-Go to the skin.
• Areas with excessive hair should be avoided or shaved to help V-Go attach to skin.

• Water activities below 3 feet, 3 inches (1 meter), such as scuba diving.
• Extremely hot water temperatures, such as hot tubs or whirlpools.

Mannkind has a team of Certified V-Go trainers who can provide complimentary V-Go step-by-step instruction by phone or video chat at a time that is convenient for your patients. Direct your patients to call 1-877-523-1199 to speak directly to a V-Go trainer or visit www.vgotraining.com to request a trainer contact them.

• The EZ Fill with an insulin vial attached should be refrigerated. Contact the insulin manufacturer regarding guidelines for travel. Pack in a secure location that is free from shaking, jarring, and impacts.
• Empty V-Go devices do not require refrigeration.
• If the patient is going on a short trip and does not wish to take their EZ Fill, they should be familiarized with all V-Go storage information.

No, V-Go must be completely filled each day to work properly.

The patient should hold the viewing window at eye level and direct the backside of the EZ Fill toward a brightly lit area. Ideally, one should see only fluid and no air space, though tiny air bubbles smaller than a grain of rice are OK.

The patient should check to make sure the insulin vial is completely pushed down into the insulin vial holder and that the EZ Fill drawer is completely closed. Also, be sure that the plunger is pulled to its full upright position, and that it is not pushed down too quickly. If the vial runs out of insulin, remove the empty vial from the EZ Fill insulin vial holder, replace with a new vial, and continue filling V-Go.

This is normal. As V-Go is filled, extra pressure may be required to push the plunger down completely.

To help maintain a consistent daily routine, V-Go should be applied immediately after filling. However, two V-Go devices may be filled with Humalog®, one for immediate use and one to replace the first V-Go after 24 hours if refrigerated or left at room temperature. Six V-Go devices may be filled with NovoLog®, one for immediate use and the other five to be used subsequently for the next 5 days if refrigerated, or four V-Go devices can be filled one for immediate use and the other three to be used subsequently for the next 3 days if left at room temperature.

Humalog is a registered trademark of Eli Lilly and Company.
NovoLog is a registered trademark of Novo Nordisk A/S.

First the patient should check that the Bolus Ready Button is fully pressed. If the Bolus Delivery Button fails to pop out after the Bolus Ready Button has been activated, then the available insulin for bolus dosing (36 Units or 18 clicks per device) has been spent. The Bolus Delivery Button is designed to pop out and lock after 18 clicks, preventing further bolus doses. If this occurs, the patient should replace the empty V-Go device with a new filled V-Go before the next meal. Patients should plan each day accordingly to ensure they have enough insulin for each meal. They may require professional guidance with planning and managing their bolus dosing as well as anticipating what to do if they run out of insulin at mealtimes.